Primary cutaneous plasmablastic lymphoma revealing clinically unsuspected HIV infection

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Primary cutaneous plasmablastic lymphoma revealing clinically unsuspected HIV infection*

Plasmablastic lymphoma is a rare subtype of diffuse large B-cell lymphoma more frequently diagnosed in immunosuppressed patients, mainly HIV-infected. Primary cutaneous plasmablastic lymphoma is extremely rare, and in this patient it was the first clinical manifestation of unsuspected HIV-infection.

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[Cutaneous presentation of plasmablastic lymphoma in a patient with HIV Infection].

firm subcutaneous nodules of between 1 cm and 3 cm in diameter on the trunk and lower limbs (Figure 1), adherent to the deep planes, and with a violaceous contusiform appearance of the overlying skin. Relevant details of the patient ’s history include previous parenteral drug use, hepatitis B virus (HBV) (surface antigen positive), hepatitis C virus (HCV), and HIV (stage B3) infection; she was ...

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Primary Maxillary Sinus Plasmablastic Lymphoma in HIV/AIDS.

Classically, the HIV/AIDS-related lymphomas are of the B cell type and involve the central nervous system and the abdominal cavity. Primary maxillary sinus lymphoma is rare. Plasmablastic lymphoma (PBL) is an aggressive form of non-Hodgkinvs lymphoma, and is extremely rare. Here we present a case of plasmablastic lymphoma with primary site being maxillary sinus, a rare location.

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Current knowledge on HIV-associated Plasmablastic Lymphoma

HIV-associated PBL is an AIDS-defining cancer, classified by WHO as a distinct entity of aggressive DLBCL. To date less than 250 cases have been published, of them 17 are pediatric. The pathogenesis of this rare disease is related to immunodeficiency, chronic immune stimulation and EBV. Clinically is a rapid growing destructive disease mainly involving the oral cavity even if extraoral and extr...

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Intraocular Plasmablastic Lymphoma in a HIV Patient

Plasmablastic lymphoma (PBL) is a rare B-cell lymphoma occurring mainly in HIV patients. The tumor frequently involves extranodal sites such as the oral cavity, nasal cavity, gastrointestinal tract, skin, and lungs. The neoplastic cells are characterized by a plasmablastic appearance and typical immunophenotype that indicates plasma cell differentiation. Herein, we report a case of intraocular ...

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ژورنال

عنوان ژورنال: Anais Brasileiros de Dermatologia

سال: 2016

ISSN: 0365-0596

DOI: 10.1590/abd1806-4841.20164764